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1

In vitro and ex vivo evaluation of an intestinal permeation enhancing self-microemulsifying drug delivery system (SMEDDS)

Hintzen, F., Laffleur, F., Sarti, F., Müller, C., Bernkop-Schnürch, A.

Journal:

Journal of Drug Delivery Science and Technology

Year:

2013

Language:

english

File:

PDF, 775 KB

english, 2013

2

Thiolated chitosan micelles: Highly mucoadhesive drug carriers

Mahmood, Arshad, Lanthaler, Melanie, Laffleur, Flavia, Huck, Christian W., Bernkop-Schnürch, Andreas

Journal:

Carbohydrate Polymers

Year:

2017

Language:

english

File:

PDF, 425 KB

english, 2017

3

In vivo evaluation of an oral self-microemulsifying drug delivery system (SMEDDS) for leuprorelin

Hintzen, Fabian, Perera, Glen, Hauptstein, Sabine, Müller, Christiane, Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2014

Language:

english

File:

PDF, 702 KB

english, 2014

4

In Vivo Evaluation of Thiolated Chitosan Tablets for Oral Insulin Delivery

Millotti, Gioconda, Laffleur, Flavia, Perera, Glen, Vigl, Claudia, Pickl, Karin, Sinner, Frank, Bernkop-Schnürch, Andreas

Journal:

Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 350 KB

english, 2014

5

Strategies for improving mucosal drug delivery

Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

Year:

2013

Language:

english

File:

PDF, 2.48 MB

english, 2013

6

In vivo evaluation of anionic thiolated polymers as oral delivery systems for efflux pump inhibition

Palmberger, Thomas F., Laffleur, Flavia, Greindl, Melanie, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 617 KB

english, 2015

7

Development of novel mucoadhesive hyaluronic acid derivate as lubricant for the treatment of dry eye syndrome

Laffleur, Flavia, Dachs, Sabrina

Journal:

Therapeutic Delivery

Year:

2015

Language:

english

File:

PDF, 1.42 MB

english, 2015

8

Nasal drug delivery: Design of a novel mucoadhesive and in situ gelling polymer

Menzel, Claudia, Jelkmann, Max, Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 935 KB

english, 2016

9

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry

Lim, Junghyun, Giri, Pankaj Kumar, Kazadi, David, Laffleur, Brice, Zhang, Wanwei, Grinstein, Veronika, Pefanis, Evangelos, Brown, Lewis M., Ladewig, Erik, Martin, Ophélie, Chen, Yuling, Rabadan, Raul,

Journal:

Year:

2017

Language:

english

File:

PDF, 8.32 MB

english, 2017

10

The RNA Exosome Syncs IAV-RNAPII Transcription to Promote Viral Ribogenesis and Infectivity

Rialdi, Alexander, Hultquist, Judd, Jimenez-Morales, David, Peralta, Zuleyma, Campisi, Laura, Fenouil, Romain, Moshkina, Natasha, Wang, Zhen Zhen, Laffleur, Brice, Kaake, Robyn M., McGregor, Michael J

Journal:

Year:

2017

Language:

english

File:

PDF, 2.79 MB

english, 2017

11

Evaluation of dermal adhesive formulations for topical application

Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2017

Language:

english

File:

PDF, 668 KB

english, 2017

12

HEC-cysteamine conjugates: Influence of degree of thiolation on efflux pump inhibitory and permeation enhancing properties

Deni Rahmat, Duangkamon Sakloetsakun, Gul Shahnaz, Federica Sarti, Flavia Laffleur, Andreas Bernkop Schnürch

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 585 KB

english, 2012

13

Thiolated chitosan nanoparticles for the nasal administration of leuprolide: Bioavailability and pharmacokinetic characterization

Gul Shahnaz, Anja Vetter, Jan Barthelmes, Deni Rahmat, Flavia Laffleur, Javed Iqbal, Glen Perera, Wolfgang Schlocker, Sarah Dünnhaput, Patrick Augustijns, Andreas Bernkop-Schnürch

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 609 KB

english, 2012

14

Development and in vivo characterization of a novel peptide drug delivery system providing extended plasma half life

Gul Shahnaz, Javed Iqbal, Deni Rahmat, Glen Perera, Flavia Laffleur, Denise Rossi, Andreas Bernkop-Schnürch

Journal:

Journal of Controlled Release

Year:

2012

Language:

english

File:

PDF, 783 KB

english, 2012

15

In situ gelling properties of anionic thiomers

Hintzen, Fabian, Laffleur, Flavia, Sakloetsakun, Duangkamon, Leithner, Katharina, Bernkop-Schnürch, Andreas

Journal:

Drug Development and Industrial Pharmacy

Year:

2012

Language:

english

File:

PDF, 823 KB

english, 2012

16

Development and in vivo evaluation of an oral vitamin B12 delivery system

Sarti, Federica, Müller, Christiane, Iqbal, Javed, Perera, Glen, Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2013

Language:

english

File:

PDF, 671 KB

english, 2013

17

Thiomers: Influence of molar mass on in situ gelling properties

Fabian Hintzen, Flavia Laffleur, Federica Sarti, Gul Shahnaz, Andreas Bernkop-Schnürch

Journal:

International Journal of Pharmaceutics

Year:

2012

Language:

english

File:

PDF, 471 KB

english, 2012

18

Development and in vitro evaluation of slippery nanoparticles for enhanced diffusion through native mucus

Laffleur, Flavia, Hintzen, Fabian, Shahnaz, Gul, Rahmat, Deni, Leithner, Katharina, Bernkop-Schnürch, Andreas

Journal:

Year:

2014

Language:

english

File:

PDF, 2.69 MB

english, 2014

19

Design and in vitro evaluation of a novel polymeric excipient for buccal applications

Laffleur, Flavia, Shahnaz, Gul, Islambulchilar, Ziba, Bernkop-Schnürch, Andreas

Journal:

Future Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 906 KB

english, 2013

20

Thiomers: promising platform for macromolecular drug delivery

Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

Future Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 2.54 MB

english, 2012

21

Efficient MRI labeling of endothelial progenitor cells: Design of thiolated surface stabilized superparamagnetic iron oxide nanoparticles

Shahnaz, Gul, Kremser, Christian, Reinisch, Andreas, Vetter, Anja, Laffleur, Flavia, Rahmat, Deni, Iqbal, Javed, Dünnhaupt, Sarah, Salvenmoser, Willi, Tessadri, Richard, Griesser, Ulrich, Bernkop-Schn

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2013

Language:

english

File:

PDF, 2.60 MB

english, 2013

22

Preactivated thiomers: Evaluation of gastroretentive minitablets

Hauptstein, Sabine, Müller, Christiane, Dünnhaupt, Sarah, Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2013

Language:

english

File:

PDF, 663 KB

english, 2013

23

Enzymatic degradation of thiolated chitosan

Laffleur, Flavia, Hintzen, Fabian, Rahmat, Deni, Shahnaz, Gul, Millotti, Gioconda, Bernkop-Schnürch, Andreas

Journal:

Drug Development and Industrial Pharmacy

Year:

2013

Language:

english

File:

PDF, 869 KB

english, 2013

24

Immunoglobulin genes undergo legitimate repair in human B cells not only after cis- but also frequent trans-class switch recombination

Laffleur, B, Bardet, S M, Garot, A, Brousse, M, Baylet, A, Cogné, M

Journal:

Genes and Immunity

Year:

2014

Language:

english

File:

PDF, 1.02 MB

english, 2014

25

HEC-cysteamine particles: influence of particle size, zeta potential, morphology and sulfhydryl groups on permeation enhancing properties

Rahmat, Deni, Müller, Christiane, Shahnaz, Gul, Leithner, Katharina, Laffleur, Flavia, Khan, Mohammad Imran, Martien, Ronny, Schnürch, Andreas Bernkop

Journal:

Drug Development and Industrial Pharmacy

Year:

2013

Language:

english

File:

PDF, 842 KB

english, 2013

26

Chemical Modification of Hyaluronic Acid for Intraoral Application

Laffleur, Flavia, Röggla, Julia, Idrees, Muneeb Ahmad, Griessinger, Julia

Journal:

Journal of Pharmaceutical Sciences

Year:

2014

Language:

english

File:

PDF, 4.42 MB

english, 2014

27

Preactivated hyaluronic acid: A potential mucoadhesive polymer for vaginal delivery

Nowak, Jessika, Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 931 KB

english, 2015

28

Mucoadhesive polymers for buccal drug delivery

Laffleur, Flavia

Journal:

Drug Development and Industrial Pharmacy

Year:

2014

Language:

english

File:

PDF, 611 KB

english, 2014

29

Self-Restrained B Cells Arise following Membrane IgE Expression

Laffleur, Brice, Duchez, Sophie, Tarte, Karin, Denis-Lagache, Nicolas, Péron, Sophie, Carrion, Claire, Denizot, Yves, Cogné, Michel

Journal:

Year:

2015

Language:

english

File:

PDF, 2.72 MB

english, 2015

30

Thiolated silicone oil: Synthesis, gelling and mucoadhesive properties

Partenhauser, Alexandra, Laffleur, Flavia, Rohrer, Julia, Bernkop-Schnürch, Andreas

Journal:

Acta Biomaterialia

Year:

2015

Language:

english

File:

PDF, 702 KB

english, 2015

31

Evaluation of functional characteristics of preactivated thiolated chitosan as potential therapeutic agent for dry mouth syndrome

Laffleur, Flavia, Fischer, Alexander, Schmutzler, Matthias, Hintzen, Fabian, Bernkop-Schnürch, Andreas

Journal:

Acta Biomaterialia

Year:

2015

Language:

english

File:

PDF, 1.24 MB

english, 2015

32

A p53 Defect Sensitizes Various Stages of B Cell Development to Lymphomagenesis in Mice Carrying an IgH 3' Regulatory Region-Driven c-myc Transgene

Fiancette, R., Rouaud, P., Vincent-Fabert, C., Laffleur, B., Magnone, V., Cogne, M., Denizot, Y.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.31 MB

english, 2011

33

AID-Driven Deletion Causes Immunoglobulin Heavy Chain Locus Suicide Recombination in B Cells

Peron, S., Laffleur, B., Denis-Lagache, N., Cook-Moreau, J., Tinguely, A., Delpy, L., Denizot, Y., Pinaud, E., Cogne, M.

Journal:

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

34

Can thiolation render a low molecular weight polymer of just 20-kDa mucoadhesive?

Mahmood, Arshad, Bonengel, Sonja, Laffleur, Flavia, Ijaz, Muhammad, Idrees, Muneeb Ahmad, Hussain, Shah, Huck, Christian W., Matuszczak, Barbara, Bernkop-Schnürch, Andreas

Journal:

Drug Development and Industrial Pharmacy

Year:

2015

Language:

english

File:

PDF, 590 KB

english, 2015

35

Thiomers: Influence of molecular mass and thiol group content of poly(acrylic acid) on efflux pump inhibition

Grabovac, Vjera, Laffleur, Flavia, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 616 KB

english, 2015

36

A potential tailor-made hyaluronic acid buccal delivery system comprising rotigotine for Parkinson's disease?

Laffleur, Flavia, Wagner, Julian, Barthelmes, Jan

Journal:

Future Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.47 MB

english, 2015

37

In vitro characterization of insulin containing thiomeric microparticles as nasal drug delivery system

Deutel, Britta, Laffleur, Flavia, Palmberger, Thomas, Saxer, Andreas, Thaler, Marlene, Bernkop-Schnürch, Andreas

Journal:

European Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 529 KB

english, 2015

38

An in-vitro exploration of permeation enhancement by novel polysulfonate thiomers

Mahmood, Arshad, Bonengel, Sonja, Laffleur, Flavia, Ijaz, Muhammad, Leonaviciute, Gintare, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 556 KB

english, 2015

39

Synthesis and in vitro characterisation of preactivated thiolated gelatin

Rohrer, Julia, Zupancic, Ozbej, Suchaoin, Wongsakorn, Netsoomboon, Kesinee, Laffleur, Flavia, Oh, Sejin, Bernkop-Schnürch, Andreas

Journal:

European Polymer Journal

Year:

2015

Language:

english

File:

PDF, 888 KB

english, 2015

40

Evaluation of the impact of multivalent metal ions on the permeation behavior of Dolutegravir sodium

Grieβinger, Julia Anita, Hauptstein, Sabine, Laffleur, Flavia, Netsomboon, Kesinee, Bernkop-Schnürch, Andreas

Journal:

Drug Development and Industrial Pharmacy

Year:

2015

Language:

english

File:

PDF, 883 KB

english, 2015

41

Preactivated thiolated nanoparticles: A novel mucoadhesive dosage form

Menzel, Claudia, Bonengel, Sonja, de Sousa, Irene Pereira, Laffleur, Flavia, Prüfert, Felix, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 471 KB

english, 2016

42

Novel in vitro transport method for screening the reversibility of P-glycoprotein inhibitors

Netsomboon, Kesinee, Laffleur, Flavia, Suchaoin, Wongsakorn, Bernkop-Schnürch, Andreas

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2016

Language:

english

File:

PDF, 636 KB

english, 2016

43

Specific impairment of proximal tubular cell proliferation by a monoclonal light chain responsible for Fanconi syndrome

El Hamel, C., Aldigier, J.-C., Oblet, C., Laffleur, B., Bridoux, F., Cogne, M.

Journal:

Nephrology Dialysis Transplantation

Year:

2012

Language:

english

File:

PDF, 385 KB

english, 2012

44

In vitro evaluation of thio-poly acrylic acid for intraoral delivery

Laffleur, Flavia, Leder, Nina, Barthelmes, Jan

Journal:

Year:

2015

Language:

english

File:

PDF, 612 KB

english, 2015

45

Design, characterization and in vitro evaluation of a novel thiolated polymer: preactivated carboxymethyl cellulose

Laffleur, Flavia, Bacher, Lukas, Netsomboon, Kesinee

Journal:

Therapeutic Delivery

Year:

2016

Language:

english

File:

PDF, 718 KB

english, 2016

46

Next generation of buccadhesive excipient: preactivated carboxymethyl cellulose

Laffleur, Flavia, Bacher, Lukas, Vanicek, Stefan, Menzel, Claudia, Muhammad, Ijaz

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 719 KB

english, 2016

47

Mucoadhesive therapeutic compositions: a patent review (2011-2014)

Laffleur, Flavia

Journal:

Expert Opinion on Therapeutic Patents

Year:

2016

Language:

english

File:

PDF, 913 KB

english, 2016

48

Development of mucoadhesive thio-carboxymethyl cellulose for application in buccal delivery of drugs

Laffleur, Flavia, Messirek, Alexie

Journal:

Therapeutic Delivery

Year:

2016

Language:

english

File:

PDF, 988 KB

english, 2016

49

Permeation Enhancement via Thiolation: In Vitro and Ex Vivo Evaluation of Hyaluronic Acid-Cysteine Ethyl Ester

Laffleur, Flavia, Psenner, Julia, Suchaoin, Wongsakorn

Journal:

Journal of Pharmaceutical Sciences

Year:

2015

Language:

english

File:

PDF, 674 KB

english, 2015

50

Mucoadhesive polymers: Synthesis and in vitro characterization of thiolated poly(vinyl alcohol)

Suchaoin, Wongsakorn, de Sousa, Irene Pereira, Netsomboon, Kesinee, Rohrer, Julia, Abad, Patricia Hoffmann, Laffleur, Flavia, Matuszczak, Barbara, Bernkop-Schnürch, Andreas

Journal:

International Journal of Pharmaceutics

Year:

2016

Language:

english

File:

PDF, 439 KB

english, 2016